Box: 38092 Braunschweig GERMANY. Telefon +49-(0)531-391-5800 Telefax +49-(0)531-391-5854. Search for more papers by this author. Institut für Mikrobiologie, TU Braunschweig Germany . (1–3)], and for the generation of gene-regulatory networks (4), i.e. Search for more papers by this author. Deutsches Institut für Erwachsenenbildung, Leibniz-Zentrum für Lebenslanges Lernen Bonn IZA Institute of Labor Economics Forschungsinstitut zur Zukunft der Arbeit GmbH (IZA) Bonn University of Bonn Rheinische Friedrich-Wilhelms-Universität Bonn Braunschweig Technische Universtität Braunschweig Technische Universtität Braunschweig Despite this importance, the molecular mechanisms mediating this process are only poorly understood in biological systems. To provide an integrated bioinformatics platform for a systems biology approach to the biology of pseudomonads in infection and biotechnology the database SYSTOMONAS (SYSTems biology of pseudOMONAS) was established. Technische Universität Braunschweig, Institut für Physikalische und Theoretische Chemie - NanoBioSciences, and Braunschweig Integrated Centre of Systems Biology (BRICS), and Laboratory for Emerging Nanometrology (LENA), Braunschweig University of Technology, Hans-Sommer-Straße 10, 38106 Braunschweig, Germany. Both viruses use the human ACE2 receptor for cell entry, recognizing it with the Receptor Binding Domain (RBD) of the S1 subunit of the viral spike (S) protein. To develop neutralizing anti-SARS-CoV-2 antibodies, antibody gene libraries from convalescent COVID-19 … Second, homology analyses lead to putative orthologous protein pairs (see section ‘Comparative Genomics’). Institut für Organische Chemie. Institut für Gebäude- und Solartechnik, Technische Universität Braunschweig - Intelligent Energy Europe The Institute for Information Systems at Technische Universität Braunschweig, Germany, focuses on research and teaching in the area of databases and information systems.. Leibniz Universität Hannover . Harnessing lymphoma epigenetics to improve therapies (article not eligible for CME credit). Klaus Brehm Institut für Hygiene und Mikrobiologie. Technische Universität Braunschweig Universitätsplatz 2 38106 Braunschweig. Genes and proteins of eight Pseudomonas species and strains are carefully annotated by the Pseudomonas community and involved genome projects (16). Interaction of Streptococcus pneumoniae with the surface of endothelial cells is mediated in blood flow via mechanosensitive proteins such as the Von Willebrand Factor (VWF). Deutschland. Thank you for submitting a comment on this article. Important Links . Our database comprises information on eight different Pseudomonas species and strains, which genomes have been completely sequenced and functionally annotated. Comparing a Pseudomonas protein of interest with other well-characterized proteins may deliver useful insights into the evolution, distribution and species specific function. Technische Universität Braunschweig, Institut für Pharmazeutische Chemie, Beethovenstraße 55, 38106 Braunschweig, Germany Fax: +49‐531‐391‐2799===Search for more papers by this author Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstraße 7, 38106 Braunschweig, Germany Search for more papers by this author Jeroen S. Dickschat Table 1 lists parts of the corresponding database content. The web server is Apache 2.0 (Author Webpage). Most enzyme information was provided by KEGG. There are various tools for metabolic network reconstruction [e.g. If the metabolic profile during one experimental condition is similar to the condition compared, data points will arrange closely to the diagonal line. The major advantage of SOAP is its up-to-dateness, since SOAP-transmitted information is corresponding to the most recent data of the consulted database. 10.06.2010 Rainer Renkawitz Both types of nodes are clickable. Sprachen und interkulturelle Kommunikation, Graduiertenschulen und Graduiertenkollegs, Fakultät Architektur, Bauingenieurwesen und Umweltwissenschaften, Fakultät für Elektrotechnik, Informationstechnik, Physik, Fakultät für Geistes- und Erziehungswissenschaften, Braunschweiger Zentrum für Systembiologie (BRICS). Several databases provide web services via SOAP, such as the major sequence databases (23–25). 38106 Braunschweig Professorin Dr. Christine Falk: Medizinische Hochschule Hannover (MHH) Institut für Transplantationsimmunologie Carl-Neuberg-Straße 1 30625 Hannover Professorin Dr. Nicole Frankenberg-Dinkel: Technische Universität Kaiserslautern Fachbereich Biologie Fachgebiet Mikrobiologie Paul-Ehrlich-Straße 23 67663 Kaiserslautern Professor Dr.-Ing. Cell-to-cell fusion is crucial for the development and propagation of most eukaryotic organisms. Arbeitspapiere des Instituts für Marketing, TU Braunschweig Foreign Languages. Here we focus on data integration for the biotechnologically and medically relevant group of bacteria, the pseudomonads. We are planning to make up for the Technical Seminar which had to be canceled in March due to the coronavirus outbreak. The focus of SYSTOMONAS is on pseudomonads and in particular Pseudomonas aeruginosa, an opportunistic human pathogen. External web services implemented on the SYSTOMONAS (S.) websites via SOAP. If your group is not listed here, please send us an email : spc@embl-hamburg.de Register. Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstrasse 7, 38106 Braunschweig, Germany . We have chosen the open source object-relational database management system PostgreSQL 8.0.3 (Author Webpage) for our database. Several tools for the analysis of stored data and for the visualization of the corresponding results are provided, enabling a quick understanding of metabolic pathways, genomic arrangements or promoter structures of interest. Medizinische Hochschule Hannover. 649 were here. Institut für Mikrobiologie. Data points are clickable and lead to the corresponding metabolite of the database (Figure 2). This poor connectivity between the two outlined approaches might be due to the fact that the required information is stored in different databases. KEGG provided metabolic reactions, compounds, glycans and pathways; PGDv2 and PRODORIC supplied protein, gene annotation, gene-regulatory and genome structure data. Technische Universität Braunschweig, Braunschweig, Germany By comparison, PseudoCyc contains 738 enzymes (version 9.6, Author Webpage). All newly detected EC numbers by metaSHARK are also indicated as ‘predicted’ in SYSTOMONAS. E-mail address: h.waetzig@tu‐braunschweig.de Technische Universität Braunschweig, Institut für Pharmazeutische Chemie, Braunschweig, Germany. If the user is interested in the prediction of transcription factor binding sites and the deduction of corresponding regulons the tool Virtual Footprint (4) can be employed. Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstraße 7, D-38106 Braunschweig, Germany. Universität Regensburg, Institut für Biochemie, Genetik und Mikrobiologie … 0313398A), BMBF for the Bioinformatics Competence Center Intergenomics (Grant No. 1 Türk-Alman Üniversitesi, Fen Fakültesi, Istanbul, Turkey Technische Universität Braunschweig, Institut für Mikrobiologie, Braunschweig, Germany unal@tau.edu.tr m.steinert@tu-bs.de. Your comment will be reviewed and published at the journal's discretion. MEET US AT THE. This work was funded by the German Bundesministerium für Bildung und Forschung (BMBF) for the National Genome Research Network (NGFN2-EP, grant no. Forscher der Technischen Universität (TU) Braunschweig sind den schwarzen Flecken in Kartoffeln auf der Spur. Institut für Konstruktionstechnik - - - 1 Server: LSF19 Imprint and privacy Accessibility Statement QIS and LSF are products of eG Claudia Choi, Richard Münch, Stefan Leupold, Johannes Klein, Inga Siegel, Bernhard Thielen, Beatrice Benkert, Martin Kucklick, Max Schobert, Jens Barthelmes, Christian Ebeling, Isam Haddad, Maurice Scheer, Andreas Grote, Karsten Hiller, Boyke Bunk, Kerstin Schreiber, Ida Retter, Dietmar Schomburg, Dieter Jahn, SYSTOMONAS — an integrated database for systems biology analysis of Pseudomonas, Nucleic Acids Research, Volume 35, Issue suppl_1, 1 January 2007, Pages D533–D537, https://doi.org/10.1093/nar/gkl823. Mikrobiologie; So finden Sie uns; Startseite; Home; Impressum; Datenschutz; Barrierefreiheit; Sitemap; suchen. University of California, Janin Heuer. (3)Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstrasse 7, Braunschweig 38106, Germany Helmholtz Centre for Infection Research, Braunschweig 38124, Germany. Institut für Zellbiologie und Biophysik. Dear students and all interested parties, we are re-designing our website and want to include you in the process. Effect of Cryptotanshinone on Measures of Rat Cardiomyocyte Oxidative Stress and Gene Activation Associated with Apoptosis. The enzyme designation of proteins was determined in three steps. Matthias Luttmann Masterand bei Institut für Raumfahrtsysteme, Technische Universität Braunschweig Braunschweig, Niedersachsen, Deutschland 33 Kontakte Braunschweiger Forscher ernten Kartoffeln für die Wissenschaft. To develop neutralizing anti-SARS-CoV-2 antibodies, antibody gene libraries from convalescent COVID-19 … Currently, the data of SYSTOMONAS along with its visualization tools and web services can be accessed freely via a web-based user interface (Author Webpage). Statistics of the metabolic network reconstruction for various Pseudomonas species in SYSTOMONAS. Additional information, such as kinetic data, operon structures or transcriptomics data are retrieved on-the-fly via web services from PRODORIC, BRENDA and KEGG (Table 2). Biozentrum Spielmannstraße 7 38106 Braunschweig, Telefon +49-(0)531-391-5800 Telefax +49-(0)531-391-5854, Braunschweiger Zentrum für Systembiologie (BRICS) Rebenring 56 38106 Braunschweig, Stellen der TU Braunschweig Jobbörse des Career Service Merchandising Sponsoring- & Spendenleistungen Drittmittelgeförderte Forschungsprojekte, Semestertermine Lehrveranstaltungen Studiengänge von A-Z Informationen für Erstsemester TUCard, Status GITZ-Dienste Handbuch für TYPO3 (Intern) Corporate Design-Toolbox (Intern) Glossar (DE-EN) Meine Daten ändern Hochschulöffentliche Bekanntmachungen, Technische Universität Braunschweig Universitätsplatz 2 38106 Braunschweig Postfach: 38092 Braunschweig Telefon: +49 (0) 531 391-0. Prof. Dr. rer. Niedersächsisches Forschungszentrum Fahrzeugtechnik, Institut für Fahrzeugtechnik, Technische Universität Braunschweig You'll find us here 01. Institut für Festkörperphysik, Wiedner Hauptstraße 8-10, 1040 Wien Tel: +43 1 58801-13801, eMail: sekretariat(at)ifp.tuwien.ac.atsekretariat(at)ifp.tuwien.ac.at the prediction of the regulation of certain genes by specific transcription factors. 1. The visualization of metabolic pathways from KEGG in SYSTOMONAS is based on GraphViz using the dot layout. Besides other research groups and our own experimental results further data are retrieved from major general data resources. Major external sources of SYSTOMONAS are KEGG [Kyoto Encyclopedia of Genes and Genomes (9)], Pseudomonas Genome Database v2 [PGDv2 (16)], PRODORIC [PROcaryotIC Database Of gene-Regulation (4)], and BRENDA (8). Moreover, 11 exemplary protein spots from one proteome experiment were entered. Angestellt, Werkstudentin am Institut für Marketing, Technische Universität Braunschweig. : ++49 931-31-46168 2. Herzlich Willkommen auf der offiziellen Facebook-Seite der TU Clausthal! Institut für Fahrzeugtechnik, Technische Universität Braunschweig Jan. 2019 –Heute 2 Jahre. 19, 79104 Freiburg, Germany. 2Zentrum für Pharmaverfahrenstechnik (PVZ), Technische Universität Braunschweig, Franz-Liszt-Straße 35A, 38106 Braunschweig, Germany. Institut für Energie- und Systemverfahrenstechnik, Technische Universität Braunschweig Professor Dr. Christoph Levin Evangelisch-Theologische Fakultät, Abteilung Altes Testament, Ludwig-Maximilians-Universität (LMU) München Institut für Mikrobiologie, Molekulare Infektionsbiologie; null, Germany; Position. Our initial focus was on metabolomics. Es werden keine Bewerbungen mehr angenommen. Kolloquium 25.11.2015, Landesamt für … Susanne ERNST of Technische Universität Braunschweig, Braunschweig | Read 10 publications | Contact Susanne ERNST Mit 'OK' verlassen Sie die Seiten der Universität Würzburg und werden zu Twitter weitergeleitet. Upon registration you will receive an e-mail for confirmation. Braunschweig und Umgebung, Deutschland Research assistant - implementation of driving tests with measuring instruments with vehicles of various categories . Logg Dich jetzt ein, um das ganze Profil zu sehen. ASAM Technical Seminar Oct 08 - 09, 2020. Technische Universität Braunschweig Fakultäten Fakultät 2: Fakultät für Lebenswissenschaften Institute der Fachrichtung Biologie Institut für Mikrobiologie - - - 1. PGD2, BioCyc, ENZYME also contributed to the functional annotation of enzymes. This work was funded by the German Bundesministerium für Bildung und Forschung (BMBF) for the National Genome Research Network (NGFN2-EP, grant no. This makes the Technische Universität the most established and traditional university in Germany. Technische Universität Hamburg Dekanat Verfahrenstechnik Eißendorfer Straße 40, 21073 Hamburg. The corresponding annotation process is described in the following sections. We need your help to improve our website! Institut für Technische Mikrobiologie. Bis 2020, Technologie Management, Technische Universität Braunschweig. We need your help to improve our website! Diese entstehen unter anderem, wenn eine… Bildnachweis: IMN/TU Braunschweig. Broad data integration is realized using SOAP interfaces for the well established databases BRENDA, KEGG and PRODORIC. Unsere Abteilungen; Unsere Lehrveranstaltungen; Braunschweiger Zentrum für Systembiologie (BRICS) Forschungsförderung; Unsere Kooperationspartner ; Stellenausschreibung; Bildnachweis: Dr. Hilger Jagau/Alle Rechte bei der TU Braunschweig Biozentrum Spielmannstraße 7 38106 Braunschweig . The main data sources of SYSTOMONAS are stored and matched in an intermediate data container ‘metabold’, which supplies data to SYSTOMONAS (Figure 3). In particular, the step of plasma membrane merger and the contributing proteins and physicochemical factors remain mostly unknown. Besides the medically relevant P.aeruginosa the genera Pseudomonas contains various important plant pathogens and biotechnologically as well as ecologically interesting species. RWTH Aachen University | Technische Universität Berlin | Technische Universität Braunschweig | Technische Universität Darmstadt | Technische Universität Dresden | Leibniz Universität Hannover | Karlsruher Institut für Technologie | Technische Universität München | Universität Stuttgart